Tuesday, December 16, 2008

Lecture - Mendelian Genetics: Theme variations

We covered the last part of chapter 3, regarding variations to the Mendelian inheritance theme:
  • Incomplete dominance
  • Codominance
  • Multiple alleles
  • Gene interactions (including epistasis)
We also started talking about chapter 4: Pedigree analyses...

Quiz #2 Qs & As:

1. State Mendel’s principle of segregation
Alleles segregate during gamete formation so that only one allele per gene will be allocated in a gamete

2. State Mendel’s principle of independent assortment
During gamete formation alleles of different genes are assorted independently from each other, so that at zygote formation all possible combinations of alleles are possible (true for genes in different chromosomes)

3. What is recombinant DNA technology?
Using restriction enzymes to isolate fragments of DNA and recombine them with other fragments (usually plasmids to transform bacteria sand clone the DNA fragment) to be studied through a variety of techniques, or used in industry applications

4. What is he goal of a pedigree analysis?
Determine who is in risk of having a genetic condition (providing that it's not obvious) and determining what is the probability of having children affected by that condition (trait)

5. What is codominance?
When two different alleles of a gene are fully expressed in the phenotype

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