Following on the pedigree analysis chapter, we discussed the advantages of using a catalog of human Mendelian traits: The Online Mendelian Inheritance In Man (OMIM) catalog, hosted by the NCBI website. In OMIM you can find a wealth of information on human traits that are inherited in a Mendelian fashion, from the symptoms of a genetic disorder and how to diagnose it, to details in the molecular genetics and published papers on the trait or disease.
Then we introduced the several modes of inheritance of human Mendelian traits.
- Autosomal - dominant and recessive
- X-linked - dominant and recessive
- Y-linked
- Mitochondrial
We described the characteristics of the autosomal and X-linked dominant modes of inheritance.
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