Tuesday, April 6, 2010

Lab 05 - Heritability (of quantitative traits)
Lab quiz 1

Today we did our lab in heritability, a calculation that can be done when dealing with quantitative traits.

Heritability: The proportion of phenotypic variation explained by genotypic variation (as opposed to environmental factors).

Broad sense heritability (H^2): Heritability taking into account all kinds of genetic interactions (additive effects of polygenes, epistasis, dominance-recessiveness, etc.)

We used finger print ridge count data to calculate the broad sense heritability of the trait. in our "population" (the class). Every student took his/her own fingerprints and did a ridge count on each one. We pooled everybody's data and proceeded with the calculation.

Narrow sense heritability (h^2)*: Heritability taking into account only the additive effects of polygenes. This measure is of interest to individuals who are interested in selection programs with the goal of shaping a population according to their interests (e.g. farmers or cattle breeders).

We used height data from students, their parents, aunts and uncles, and siblings, to calculate h^2 in a human population, since we had the data available. This kind of heritability is usually not calculated in humans.

*Actually performed a week later, on April 13.
----------------------

Lab quiz 1

During the last hour of today's lab students took the first lab quiz.

----------------------

No comments: