Monday, January 25, 2010

Lecture, chapter 11 - Mutation

Today we finished the chapter on mutation.

Our main foci were types of mutations at the nucleotide sequence level, such as nucleotide substitutions, insertions and deletions (a.k.a. "indels"), and allelic expansions.

We also discussed the mechanisms that have evolved to correct DNA changes and prevent them from being fixed as mutations: The DNA proofreading mechanism of DNA polymerase and DNA repair (process in which many enzymes are involved).

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